Rotavirus A infection among children in Nepal | BMC Infectious Diseases - MD Linx

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Researchers performed a hospital-based cross-sectional study among children less than 5 years of age attending Kanti Children’s Hospital and Tribhuvan University Teaching Hospital collecting information associated with rotavirus gastroenteritis and performing genotyping of rotavirus A. They analyzed a total of 1,074 collected stool samples from 770 hospitalized, and 304 non-hospitalized cases. Twenty-eight percent of children had rotavirus A infection; hospitalized (34%) vs non-hospitalized (14%) children had a higher rotavirus A infection rate. Throughout the year, the occurrence of rotavirus A infection was noted, however, during the month of March, the infection occurred at a significantly higher rate. Children who were 0-23 months of age showed a higher frequency of rotavirus infection, though this was not statistically significant. In this study, they identified G12P[6] as the predominant genotype seen. For the introduction of rotavirus vaccine in Nepal, the results of genotyping are necessary.

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