Gastrointestinal Diseases from Animals

The top stories in gastroenterology last week were from Digestive Disease Week and included a study that found prophylactic placement of hemoclips following the removal of large colon polyps did not decrease the risk for post-polypectomy bleeding and results from the VARSITY study that showed clinical and endoscopic outcomes of Entyvio treatment were superior to those of Humira in moderately to severely active ulcerative colitis at 1 year. Other highlights were findings that indicated patients at risk for non-alcoholic steatohepatitis are under-recognized in primary care, a study that found data collected from activity trackers can help predict elevated biomarkers of inflammation in inflammatory bowel disease and results from the ICON study that demonstrated fecal microbiota transplantation was safe and effective in patients with inflammatory bowel disease and Clostridioides difficile infection. Hemoclips may not reduce post-polypectomy bleeding SAN DIEGO — Prophylactic placement

[unable to retrieve full-text content] Upper Gastrointestinal Disorders | Gastroenterology    Consultant360 Researchers evaluated data from more than 200,000 new users of histamine H2 receptor antagonists or proton pump inhibitors to estimate all-cause mortality ... http://bit.ly/2XdF0Ix

Advertisement In patients with multidrug-resistant chronic hepatitis B virus (HBV) infections, researchers examined the effectiveness of tenofovir disoproxyl fumarate (TDF) monotherapy and TDF-based combination therapy for viral suppression as rescue therapy by conducting a multicenter, prospective, real-world cohort study. From eight tertiary hospitals in Korea, patients with chronic HBV infection resistant to antivirals were recruited. In total, 174 patients were treated with TDF monotherapy and 249 were treated with combination therapy based on TDF. In the majority of patients with MDR who received TDF monotherapy or TDF-based combination therapy during long-term follow-up, a virologic response (defined as a serum HBV DNA level of <20 IU/mL) was achieved, and the rates were not significantly different. In patients with MDR, long-term use of TDF monotherapy demonstrated non-inferior antiviral efficacy vs that of TDF-based combination therapy. Read the full article on Clinic

[unable to retrieve full-text content] Rotavirus A infection among children in Nepal | BMC Infectious Diseases    MD Linx Infectious Disease Article: Acute gastroenteritis associated with Rotavirus A among children less than 5 years of age in Nepal. http://bit.ly/2YMTf7A

[embedded content] Mayo Clinic gastroenterologist Robert Huebert, M.D., discusses a board-style question on liver lesions with attendees at the 2018 Mayo Clinic Gastroenterology & Hepatology Board Review. Register now for the 2019 course in Chicago, September 5-8: https://mayocl.in/2YVkKvJ The Mayo Clinic Gastroenterology and Hepatology Board Review is designed for candidates preparing for certification and maintenance of certification (MOC) examinations in gastroenterology and hepatology. The Gastroenterology and Hepatology Board Review will include relevant topics such as pathology, endoscopy, radiology and nutrition. Course Highlights - Access to course recordings until the spring exam with registration - Mayo Clinic experts deliver the most comprehensive and time-efficient review available - Earn more than 30 ABIM MOC points with your CME credit - Receive a comprehensive list of high-yield facts with daily review - Obtain Mayo Clinic study materials including a 100+ qu

Healio Gastroenterology and Liver Disease has compiled a list of some of the top stories we reported in May. Our readers were most interested in a biologic license application for a subcutaneous ulcerative colitis treatment, as well as results of a study involving fecal microbiota transplantation and its role in hospital costs associated with Clostridioides difficile infection. FDA accepts application for subcutaneous Entyvio for ulcerative colitis The FDA accepted a biologic license application for a subcutaneous formulation of Entyvio for maintenance therapy in adults with moderately-to-severely active ulcerative colitis, according to a company press release. “Acceptance of this regulatory submission for review brings us one step closer to our goal of better meeting the diverse needs of patients with ulcerative colitis in the U.S.,” Uthra Sundaram, senior vice president of the GI business unit at Takeda Pharmaceuticals U.S.A., said in the release. “The availability of a subc

[unable to retrieve full-text content] Efficacy and safety of tenofovir disoproxyl fumarate monotherapy | Clinical Gastroenterology and Hepatology    MD Linx Gastroenterology Article: Long-term efficacy of tenofovir disoproxil fumarate monotherapy for multidrug-resistant chronic HBV infection. http://bit.ly/2WfL9aI

SINGAPORE - More than 50 people fell ill after eating food provided by food caterer Elsie's Kitchen in February, resulting in its food hygiene grade cut to "C" last Friday (May 24). In a notice on its website, the Singapore Food Agency (SFA) said that 52 people reported gastroenteritis symptoms after consuming food from Elsie's Kitchen on Feb 1. Following investigations, SFA adjusted the food caterer's hygiene grade with effect from last Friday, adding that it would be reviewed after a year. The premises at 21 Second Chin Bee Road would be kept under surveillance in the meantime, said SFA. The SFA website records showed that the caterer previously held an "A" food hygiene grade. According to the caterer's website, Elsie's Kitchen has been operating since 1954 and caters to more than 20,000 meals daily on average. It is a halal-certified catering company offering services for weddings, barbecues, tea receptions, corporate buffets

Wastewater continues to flow directly into the Stillwater River due to the failure of two Montgomery County sewer system lift stations that lost power after being pummeled by a tornado Monday night. Had the wastewater not been redirected into the river, the result would have been sewer backups in area homes and businesses resulting in more problems, said Brianna Wooten, the county’s communications director. “Then you have an additional public health and sewer backup crisis on top of a water crisis or an outage crisis,” she said. FIRST REPORT: Stay out of the Stillwater, Great Miami rivers: Blame the tornadoes Power crews were able to reach the lift stations Wednesday to remove downed lines. The county is currently clearing debris and will assess the structures. The Ohio EPA was notified of the bypass. Public Health – Dayton & Montgomery County issued an advisory Tuesday to not enter the Stillwater River nor the Great Miami River downstream due to the increased health risks

Royal Hobart Hospital infection control staff are working to control an outbreak of norovirus on the Children's Ward, RHH infection prevention and control medical adviser Tara Anderson said. Norovirus causes acute gastroenteritis and circulates in the community, where it can be brought into sites such as hospitals and nursing homes. At the RHH, a "small number" of patients have been isolated until they recover from the virus, and visitation to the Children's Ward has been restricted to immediate family and essential visitors. Ms Anderson said anyone who experiences gastroenteritis symptoms should not to visit a healthcare facility for at least 48 hours after their symptoms have stopped. Even if they feel relatively well they may still be able to spread the virus, she said. IN OTHER NEWS: "While norovirus outbreaks are not uncommon, the symptoms can pose a risk to patients who are already unwell and are in hospital, and additional cleaning programs need to be put

Written by Rachel Popa | May 30, 2019 | Print  | Email Here are the five most popular gastroenterology articles posted on Becker's ASC Review this week: 1. 3 key ways gastroenterologists can avoid burnout 2. To screen or not to screen? 45 is the question 3. 10 statistics to know on GI wealth, debt, salary & revenue generated for hospitals 4. States that expanded Medicaid increased CRC screening — 4 insights 5. How endoscopy pricing varies between ASCs, HOPDs in Virginia — 20 insights More articles on gastroenterology: $130M private equity deal to unite 3 GI practices, create 7th largest group in US Fujifilm building new endoscopy manufacturing plant & more: 3 GI company key notes Fujifilm's $36M endoscope plant to double production capacity — 3 insights © Copyright ASC COMMUNICATIONS 2019. Interested in LINKING to or REPRINTING this content? View our policies by clicking here . To receive the latest hospital and health system business and legal news an

[unable to retrieve full-text content] Pharmacy Conference: 52nd Annual Meeting of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) - Glasgow June 5-8, 2019    MD Linx Every year the ESPGHAN Annual Meeting attracts the key opinion leaders in the field of pediatric gastroenterology, hepatology and nutrition from Europe and all ... http://bit.ly/2JNejqZ

SAN DIEGO — Patients with Crohn’s disease who were perioperatively managed with an enhanced recovery protocol experienced a reduction in length of stay and faster recovery without an increase in adverse events, according to a study presented at Digestive Disease Week. “The basic goal of enhanced recovery protocols is to reduce the length of hospital stay and accelerate the hospital course while not increasing the risk of complications,” Donald Ha e ring , a third-year medical student at the University of Washington, Seattle, told Healio Gastroenterology . “Enhanced recovery protocols have been used in colorectal surgery in general for quite some time now.” “The paradigm has been that inflammatory bowel disease is more complicated and some surgeons have felt that perhaps patients with IBD are inappropriate for enhanced recovery protocols,” he added. “Some studies have shown that enhanced recovery protocols lead to less complicated hospital courses, so we wanted to characterize the

Every year at the Digestive Disease Week, a seemingly endless number of posters and presentations examine the use of just as many treatments for disease in gastroenterology. This year was no different and one of the more talked about treatments was etrasimod, which is a treatment, from Arena Pharmaceuticals, that has therapeutic potential in a number of conditions including ulcerative colitis, Crohn’s disease, and atopic dermatitis. Preston Klassen, MD, MHS, executive vice president and head of research and development at Arena, sat down with MD Magazine® at DDW 2019 to discuss the potential uses for etrasimod and how large of a role patient compliance plays when creating new treatments. [embedded content] MD Mag: What are some of the potential uses for etrasimod outside of irritable bowel syndrome/inflammatory bowel disease? Klassen: While we are initiating our investigation with etrasimod. in the GI space with inflammatory bowel disease, ulcerative colitis, and Crohn's dis

SAN DIEGO — Pediatric patients with ulcerative colitis who displayed a rapid drop-off of fecal calprotectin levels in the first 12 weeks of treatment experienced better 1-year outcomes, according to research presented at Digestive Disease Week. Chenthan Krishnakumar, MD, of the division of pediatric gastroenterology at Emory University, said physicians regularly use fecal calprotectin to monitor inflammation in patients with UC, but little research has focused on how early levels relate to week 52 outcomes. “Our aims are to determine if baseline fecal calprotectin at diagnosis predicts week 52 clinical outcome in UC in children ,” he said in his presentation. “And to determine if early changes in fecal calprotectin — week 4 and/or week 12 compared with baseline — following initial therapy predict week 52 clinical outcome in UC in children.” Researchers analyzed data from the PROTECT study, which comprised 248 children with newly diagnosed moderate-to-severe UC (mean age 13 years

A couple claimed they were served raw chicken on a Jet2 holiday - which left one of them sick in bed for five days. Jo Ferns took a photo showing the apparently undercooked chicken dish served at their hotel in Rhodes, in Greece . Her partner, Darren Mciver, ate the chicken at the Lindos Sun Hotel two days earlier and blames it for a crippling bout of acute gastroenteritis. The couple, from Wirral, Merseyside, paid £1,200 for their break at the four star hotel.  Jet2 say there is nothing to suggest food at the hotel caused illness.  Jo Ferns took a picture showing the apparently undercooked chicken dish (pictured) served at their hotel in Rhodes Jet2 have denied the claims the food made Darren ill. The couple, from Wirral, Merseyside, paid £1,200 for their break at the four star hotel Jo, 44, took to Jet2's Facebook page to complain, writing: 'I have no words for the response from Jet2 when I provided proof of the raw chicken served at our hotel and the doc

This 4-year-old black labrador retriever is one of a couple long-term residents at the shelter. He's playful, energetic and is full of smiles. Nicole Facciotto with Animal Allies says he has bowel problems that requires life-long medication. She says the 4-year-old takes it well each day. Animal Allies' " Walk for Animals and Furry 5K " is coming up on Saturday, June 1. Organizers say there will be activities for people of all ages. "We've got a petting zoo, food vendors, an agility course, a cutest animal contest," Facciotto says.  Registration for the 5K begins at 9 a.m. All money raised will go back to the care of the animals at the Duluth shelter. WDIO is a proud sponsor of this event. If you'd like to adopt Boe, visit Animal Allies at 4006 Airport Road or give them a call at 218-722-5341.  Click here  to see more animals available for adoption. http://bit.ly/2XeGNwU

[unable to retrieve full-text content] Palliative Care for Cirrhosis    Gastroenterology & Endoscopy News For Mina O. Rakoski, MD, a transplant hepatologist, palliative care for patients with cirrhosis can optimize quality of life by helping clinicians to anticipate, prevent ... http://bit.ly/30Mzsa2

Written by Eric Oliver | May 30, 2019 | Print  | Email Regional GI, Main Line Gastroenterology Associates and Digestive Disease Associates will merge in a $130 million deal with private equity firm Amulet Capital, PE Hub reports. What you should know: 1. Amulet Capital is uniting the groups through the deal, creating the 7th largest physician group in the U.S. The deal follows analyst predictions that PE firms would target midsize GI groups. 2. Regional GI has four Pennsylvania locations in Lancaster, Elizabethtown and Ephrata and 23 clinicians. 3. Malvern, Pa.-based Main Line Gastroenterology Associates has seven offices, three endoscopy centers and 20 clinicians. 4. Wyomissing, Pa.-based Digestive Disease Associates has four practices, two surgery centers and 19 clinicians. 5. Amulet's deal is the fourth such in gastroenterology. Several analysts predicted a significant boom in GI-focused PE investment in 2019. More articles on gastroenterology:  The biggest opportu

Advertisement Researchers performed a hospital-based cross-sectional study among children less than 5 years of age attending Kanti Children’s Hospital and Tribhuvan University Teaching Hospital collecting information associated with rotavirus gastroenteritis and performing genotyping of rotavirus A. They analyzed a total of 1,074 collected stool samples from 770 hospitalized, and 304 non-hospitalized cases. Twenty-eight percent of children had rotavirus A infection; hospitalized (34%) vs non-hospitalized (14%) children had a higher rotavirus A infection rate. Throughout the year, the occurrence of rotavirus A infection was noted, however, during the month of March, the infection occurred at a significantly higher rate. Children who were 0-23 months of age showed a higher frequency of rotavirus infection, though this was not statistically significant. In this study, they identified G12P[6] as the predominant genotype seen. For the introduction of rotavirus vaccine in Nepal, the resu

Chick-fil-A is now using AI to monitor social media feedback from customers in order to detect and prevent foodborne illness, QSR reports . At last week’s ReWork Deep Learning Summit in Boston, Chick-fil-A’s senior principle IT leader of food safety and product quality, Davis Addy, explained how this tech works. For most QSRs, gathering feedback from social media is key for getting insights into what’s working and what isn’t with the business. That includes spotting any mentions of food safety issues or potential foodborne illnesses like norovirus, which on average causes 19–21 million cases of acute gastroenteritis annually in the U.S. Restaurants and catered events are one of the most common settings for norovirus, according to the CDC . But to find these mentions, Chick-fil-A (or any QSR, for that matter) has to sift through hundreds if not thousands of customer reviews every day, many of them written with poor (or no) grammar and what Addy called “mixed sentiments and off-top

MONTGOMERY COUNTY — Stay out of the Stillwater and Great Miami rivers -- and don't fish in either body of water -- until further notice.  Why? Wastewater. Montgomery County Environmental Services, because of the widespread power outages brought on by the Memorial Day tornadoes, has begun to temporarily redirect wastewater into the Stillwater in Montgomery County to minimize damage to private property and residences. The Ohio EPA has been notified of the bypass.  Content Continues Below The suggestion is precautionary, officials with Public Health Dayton & Montgomery County said in a statement Tuesday night.  There are increased health risks associated with coming into contact with wastewater.  Parasites, viruses and bacteria can cause a range of conditions including diarrhea, dysentery, gastroenteritis and hepatitis A.  To prevent the spread of disease, Public Health is advising you not to enter the wastewater until the water diversion has ended.  Swallowing a small

[unable to retrieve full-text content] Palliative Care for Cirrhosis    Gastroenterology & Endoscopy News For Mina O. Rakoski, MD, a transplant hepatologist, palliative care for patients with cirrhosis can optimize quality of life by helping clinicians to anticipate, prevent ... http://bit.ly/2wu5SZ4

May 29 is World Digestive Health Day. Created in 2003 to commemorate the 45th anniversary of the establishment of the World Gastroenterology Organisation, World Digestive Health Day aims to raise awareness and provide resources and tools for gastrointestinal diseases and disorders. Each year the WGO selects a specific campaign focus for World Digestive Health Day. The last two years focused on inflammatory bowel disease and viral hepatitis. This year, the campaign is emphasizing gastrointestinal cancers. The aim of this year’s WDHD, according to a statement from the co-chairs, is to raise awareness for the early diagnosis and treatment of GI cancer through its annual public advocacy and awareness campaign. In recognition of WDHD, Healio Gastroenterology and Liver Disease has compiled a list of seven updates on topics involving GI cancers, including a video-based polypectomy training tool. Endoscopic resection cost-effective for benign rectal polyps Endoscopic resection with care

Investment Thesis Pfizer (NYSE: PFE ) is a large-cap ($232B) global biopharmaceutical company widely known for the development of the blockbuster cardiovascular drug, Lipitor. Lipitor is perhaps the most recognized statin drug that is used clinically and over the counter to lower bad cholesterol, LDL-C. Pfizer is also a proven pioneer of therapeutics for HIV infection, autoimmune, and gastrointestinal diseases as well as hematological and oncological ailments. Presently, it is clinically assessing the therapeutic effects of small drug molecules targeting the fibrotic liver disease, NASH. Although a late-starter to clinically developing its NASH pipeline, Pfizer is now moving full speed with its NASH monotherapy and combination therapeutic clinical programs. There are three in-house drug candidates in clinical trials for NASH and/or NAFLD. Pfizer is developing lead asset, PF-05221304, an Acetyl-CoA carboxylase (ACC) inhibitor; PF-06835919, a Ketohexokinase (KHK) Inhibitor and PF-06865

May 29 is World Digestive Health Day. Created in 2003 to commemorate the 45th anniversary of the establishment of the World Gastroenterology Organisation, World Digestive Health Day aims to raise awareness and provide resources and tools for gastrointestinal diseases and disorders. Each year the WGO selects a specific campaign focus for World Digestive Health Day. The last two years focused on inflammatory bowel disease and viral hepatitis. This year, the campaign is emphasizing gastrointestinal cancers. The aim of this year’s WDHD, according to a statement from the co-chairs, is to raise awareness for the early diagnosis and treatment of GI cancer through its annual public advocacy and awareness campaign. In recognition of WDHD, Healio Gastroenterology and Liver Disease has compiled a list of seven updates on topics involving GI cancers, including a video-based polypectomy training tool. Endoscopic resection cost-effective for benign rectal polyps Endoscopic resection with care

SAN DIEGO — Starting college can be tough for anyone, but students with inflammatory bowel disease have a greater risk for poor adjustment to college life, according to results of a prospective study presented at Digestive Disease Week. Angela Pham, MD, of the division of gastroenterology at University of Florida, said the transition from pediatric to adult care in IBD is often poorly managed and comes at difficult point of life for patients, making them vulnerable to poorer outcomes. “Transition usually occurs during the college years, and little is known about the college experience for youth living with chronic illness like IBD,” Pham said in her presentation. “Understanding why there are barriers to IBD students’ adjustment to college helps optimize the care of adolescent IBD patients.” Researchers performed a prospective study to understand how these patients manage their disease and how it impacts their life in college. They used a cohort of 135 individuals, including 59 pa

Eating the right food throughout your workday is as essential as filling your car up with gas. Without it, you get nowhere. Moreover, the quality of fuel matters. A poor diet is like filling your gas tank with sugary  Pepsi . In short, food affects not just how we feel and what we weigh; it changes how we work. Here are three tips to eat your way to a better workday, based on scientific research and real insights from employer reviews on  kununu. Follow Ladders’ magazines on Flipboard covering Happiness , Productivity , Job Satisfaction , Neuroscience , and more ! Breakfast actually matters Breakfast fuels the most energetic, inspired part of our workday. Research shows that alertness spikes right after breakfast is consumed. A good breakfast is the difference between a lethargic, unproductive morning, and one of those unstoppable, “in-the-zone” mornings. What breakfast is best? High fiber, carb-rich meals are associated with the highest alertness ratings, as well as the most cu